MON-217 Maternal Androgen Excess and Obesity Induce Cardiac Hypertrophy and Left Ventricular Dysfunction in Female Offspring

Polycystic ovary syndrome (PCOS) is suggested to increase the risk for cardiovascular disease and type 2 diabetes. We hypothesized here that prenatal exposure to dihydrotestosterone (DHT) and/or maternal obesity lead to adverse metabolic and cardiac programming in the female offspring. The maternal...

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Bibliografiska uppgifter
I publikationen:J Endocr Soc
Huvudupphovsmän: Manti, Maria, Fornes, Romina, Pironti, Gianluigi, McCann Haworth, Sarah, Zhuge, Zhengbing, Lindén Hirschberg, Angelica, De Castro Barbosa, Thais, Benrick, Anna, Carlström, Mattias, Andersson, Daniel, Stener-Victorin, Elisabet
Materialtyp: Artigo
Språk:Inglês
Publicerad: Endocrine Society 2019
Ämnen:
Reproductive Endocrinology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551113/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-MON-217
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