MON-217 Maternal Androgen Excess and Obesity Induce Cardiac Hypertrophy and Left Ventricular Dysfunction in Female Offspring

Polycystic ovary syndrome (PCOS) is suggested to increase the risk for cardiovascular disease and type 2 diabetes. We hypothesized here that prenatal exposure to dihydrotestosterone (DHT) and/or maternal obesity lead to adverse metabolic and cardiac programming in the female offspring. The maternal...

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Bibliografiske detaljer
Udgivet i:J Endocr Soc
Main Authors: Manti, Maria, Fornes, Romina, Pironti, Gianluigi, McCann Haworth, Sarah, Zhuge, Zhengbing, Lindén Hirschberg, Angelica, De Castro Barbosa, Thais, Benrick, Anna, Carlström, Mattias, Andersson, Daniel, Stener-Victorin, Elisabet
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2019
Fag:
Reproductive Endocrinology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551113/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-MON-217
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