MON-538 Ca(2+)Allostery in PTH-Receptor Signaling

The parathyroid hormone (PTH) type 1 receptor (PTHR) serves as the cognate receptor for two endogenous ligands, PTH and its related peptide (PTHrP). Binding of PTHrP to the PTHR results in only transient cAMP production that is limited to the plasma membrane, while PTH induces sustained cAMP respons...

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Detaylı Bibliyografya
Yayımlandı:J Endocr Soc
Asıl Yazarlar: White, Alex, Sutkeviciute, Ieva, Jean-Alphonse, Frederic, Xiao, Kunhong, Vilardaga, Jean-Pierre
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Endocrine Society 2019
Konular:
Bone and Mineral Metabolism
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551044/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-MON-538
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