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MON-538 Ca(2+)Allostery in PTH-Receptor Signaling

The parathyroid hormone (PTH) type 1 receptor (PTHR) serves as the cognate receptor for two endogenous ligands, PTH and its related peptide (PTHrP). Binding of PTHrP to the PTHR results in only transient cAMP production that is limited to the plasma membrane, while PTH induces sustained cAMP respons...

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Dades bibliogràfiques
Publicat a:J Endocr Soc
Autors principals: White, Alex, Sutkeviciute, Ieva, Jean-Alphonse, Frederic, Xiao, Kunhong, Vilardaga, Jean-Pierre
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551044/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-MON-538
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