MON-100 Unique miRNA Signature in HIV Lipodystrophy with Reduced Adipose Dicer Expression

Suppression of Dicer, an endoribonuclease that regulates microRNAs(miRNA), has evolved as a viral mechanism to enhance host HIV infectivity and may have unintended metabolic consequences. Animal knockout models of adipose-specific dicer(ADicer) acquire lipodystrophy accompanied by severe metabolic a...

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Publicat a:J Endocr Soc
Autors principals: Srinivasa, Suman, Garcia, Ruben, Torriani, Martin, Fitch, Kathleen, Maehler, Patrick, Feldpausch, Meghan, Cypess, Aaron, Kahn, Carl, Grinspoon, Steven
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2019
Matèries:
Adipose Tissue, Appetite, and Obesity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550730/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-MON-100
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