Altered miRNA processing disrupts brown/white adipocyte determination and associates with lipodystrophy

miRNAs are important regulators of biological processes in many tissues, including the differentiation and function of brown and white adipocytes. The endoribonuclease dicer is a major component of the miRNA-processing pathway, and in adipose tissue, levels of dicer have been shown to decrease with...

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Autores principales: Mori, Marcelo A., Thomou, Thomas, Boucher, Jeremie, Lee, Kevin Y., Lallukka, Susanna, Kim, Jason K., Torriani, Martin, Yki-Järvinen, Hannele, Grinspoon, Steven K., Cypess, Aaron M., Kahn, C. Ronald
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109560/
https://ncbi.nlm.nih.gov/pubmed/24983316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73468
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