Differential requirements of protein geranylgeranylation for the virulence of human pathogenic fungi

Protein prenylation is a crucial post-translational modification largely mediated by two heterodimeric enzyme complexes, farnesyltransferase and geranylgeranyltransferase type-I (GGTase-I), each composed of a shared α-subunit and a unique β-subunit. GGTase-I enzymes are validated drug targets that c...

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Detalles Bibliográficos
Publicado en:Virulence
Main Authors: Souza, Ana Camila Oliveira, Al Abdallah, Qusai, DeJarnette, Kaci, Martin-Vicente, Adela, Nywening, Ashley V., DeJarnette, Christian, Sansevere, Emily A., Ge, Wenbo, Palmer, Glen E., Fortwendel, Jarrod R
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2019
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550545/
https://ncbi.nlm.nih.gov/pubmed/31131706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2019.1620063
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