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Differential requirements of protein geranylgeranylation for the virulence of human pathogenic fungi
Protein prenylation is a crucial post-translational modification largely mediated by two heterodimeric enzyme complexes, farnesyltransferase and geranylgeranyltransferase type-I (GGTase-I), each composed of a shared α-subunit and a unique β-subunit. GGTase-I enzymes are validated drug targets that c...
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| 出版年: | Virulence |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6550545/ https://ncbi.nlm.nih.gov/pubmed/31131706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2019.1620063 |
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