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Optical sensor revealed abnormal nuclease spatial activity on cancer cell membrane

Nucleases are important enzymes that cleave nucleic acids and play critical roles in DNA repair, immune defense and potentially in cancer invasion. However, their spatial dynamics at subcellular level is much less studied. Here, we developed a surface‐tethered nuclease sensor (SNS) which directly co...

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Библиографические подробности
Опубликовано в: :J Biophotonics
Главные авторы: Wang, Yongliang, Zhao, Yuanchang, Sarkar, Anwesha, Wang, Xuefeng
Формат: Artigo
Язык:Inglês
Опубликовано: WILEY‐VCH Verlag GmbH & Co. KGaA 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550314/
https://ncbi.nlm.nih.gov/pubmed/30488667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbio.201800351
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