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Optical sensor revealed abnormal nuclease spatial activity on cancer cell membrane

Nucleases are important enzymes that cleave nucleic acids and play critical roles in DNA repair, immune defense and potentially in cancer invasion. However, their spatial dynamics at subcellular level is much less studied. Here, we developed a surface‐tethered nuclease sensor (SNS) which directly co...

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Detalhes bibliográficos
Publicado no:J Biophotonics
Main Authors: Wang, Yongliang, Zhao, Yuanchang, Sarkar, Anwesha, Wang, Xuefeng
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY‐VCH Verlag GmbH & Co. KGaA 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550314/
https://ncbi.nlm.nih.gov/pubmed/30488667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbio.201800351
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