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Cochaperone binding to LYR motifs confers specificity of iron sulfur cluster delivery

Iron-sulfur (Fe-S) clusters, pre-assembled on the ISCU scaffold, are transferred to target proteins or to intermediate scaffolds by a dedicated chaperone-cochaperone system. However, the molecular mechanisms that underlie substrate discrimination and guide delivery of nascent clusters to specific su...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Metab
Prif Awduron: Maio, Nunziata, Singh, Anamika, Uhrigshardt, Helge, Saxena, Neetu, Tong, Wing-Hang, Rouault, Tracey A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550293/
https://ncbi.nlm.nih.gov/pubmed/24606901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.01.015
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