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Cochaperone binding to LYR motifs confers specificity of iron sulfur cluster delivery
Iron-sulfur (Fe-S) clusters, pre-assembled on the ISCU scaffold, are transferred to target proteins or to intermediate scaffolds by a dedicated chaperone-cochaperone system. However, the molecular mechanisms that underlie substrate discrimination and guide delivery of nascent clusters to specific su...
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| Veröffentlicht in: | Cell Metab |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6550293/ https://ncbi.nlm.nih.gov/pubmed/24606901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.01.015 |
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