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Pharmacokinetic study of the oral fluorouracil antitumor agent S‐1 in patients with impaired renal function

Although dose reduction of S‐1 is recommended for patients with impaired renal function, dose modification for such patients has not been prospectively evaluated. The aim of the present study was to investigate the pharmacokinetic parameters of 5‐fluorouracil, 5‐chloro‐2,4 dihydroxypyridine and oter...

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Détails bibliographiques
Publié dans:Cancer Sci
Auteurs principaux: Goto, Keiko, Fujiwara, Yutaka, Isobe, Takeshi, Chayahara, Naoko, Kiyota, Naomi, Mukohara, Toru, Tsubata, Yukari, Hotta, Takamasa, Tamura, Kenji, Yamamoto, Noboru, Minami, Hironobu
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550132/
https://ncbi.nlm.nih.gov/pubmed/30989775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14025
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