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Pharmacokinetic study of the oral fluorouracil antitumor agent S‐1 in patients with impaired renal function

Although dose reduction of S‐1 is recommended for patients with impaired renal function, dose modification for such patients has not been prospectively evaluated. The aim of the present study was to investigate the pharmacokinetic parameters of 5‐fluorouracil, 5‐chloro‐2,4 dihydroxypyridine and oter...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Goto, Keiko, Fujiwara, Yutaka, Isobe, Takeshi, Chayahara, Naoko, Kiyota, Naomi, Mukohara, Toru, Tsubata, Yukari, Hotta, Takamasa, Tamura, Kenji, Yamamoto, Noboru, Minami, Hironobu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550132/
https://ncbi.nlm.nih.gov/pubmed/30989775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14025
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