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Apoptosis and oxidative stress as relevant mechanisms of antitumor activity and genotoxicity of ZnO-NPs alone and in combination with N-acetyl cysteine in tumor-bearing mice

Background: Several in vitro studies have revealed that zinc oxide nanoparticles (ZnO-NPs) were able to target cancerous cells selectively with minimal damage to healthy cells. Purpose: In the current study, we aimed to evaluate the antitumor activity of ZnO-NPs in Ehrlich solid carcinoma (ESC) bear...

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Dettagli Bibliografici
Pubblicato in:Int J Nanomedicine
Autori principali: El-Shorbagy, Haidan M, Eissa, Shaymaa M, Sabet, Salwa, El-Ghor, Akmal A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549730/
https://ncbi.nlm.nih.gov/pubmed/31213808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S204757
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