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Bone marrow derived-mesenchymal stem cells downregulate IL17A dependent IL6/STAT3 signaling pathway in CCl(4)-induced rat liver fibrosis

Therapeutic potential of bone marrow–derived mesenchymal stem cells (BM-MSCs) has been reported in several animal models of liver fibrosis. Interleukin (IL) 17A, IL6 and Stat3 have been described to play crucial roles in chronic liver injury. However, the modulatory effect of MSCs on these markers w...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Farouk, Shimaa, Sabet, Salwa, Abu Zahra, Fatma A., El-Ghor, Akmal A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197688/
https://ncbi.nlm.nih.gov/pubmed/30346985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206130
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