Design of a prospective observational study on the effectiveness and real-world usage of recombinant factor VIII Fc (rFVIIIFc) compared with conventional products in haemophilia A: the A-SURE study

INTRODUCTION: Haemophilia A is a rare bleeding disorder caused by coagulation factor VIII (FVIII) deficiency. This is treated with factor VIII, conventionally using products with a half-life of 8–12 hours typically administered every 2–3 days. Recombinant FVIII Fc (rFVIIIFc) represents a new generat...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Oldenburg, Johannes, Hay, Charles R M, Jiménez-Yuste, Víctor, Peyvandi, Flora, Schved, Jean-François, Szamosi, Johan, Winding, Bent, Lethagen, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Haematology (Incl Blood Transfusion)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549707/
https://ncbi.nlm.nih.gov/pubmed/31152037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2018-028012
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