Genomic characterization of a well-differentiated grade 3 pancreatic neuroendocrine tumor

Pancreatic neuroendocrine neoplasms (PanNENs) represent a minority of pancreatic neoplasms that exhibit variability in prognosis. Ongoing mutational analyses of PanNENs have found recurrent abnormalities in chromatin remodeling genes (e.g., DAXX and ATRX), and mTOR pathway genes (e.g., TSC2, PTEN PI...

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Pubblicato in:Cold Spring Harb Mol Case Stud
Autori principali: Williamson, Laura M., Steel, Michael, Grewal, Jasleen K., Thibodeau, My Lihn, Zhao, Eric Y., Loree, Jonathan M., Yang, Kevin C., Gorski, Sharon M., Mungall, Andrew J., Mungall, Karen L., Moore, Richard A., Marra, Marco A., Laskin, Janessa, Renouf, Daniel J., Schaeffer, David F., Jones, Steven J.M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549554/
https://ncbi.nlm.nih.gov/pubmed/31160355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a003814
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