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Molecular characterization of metastatic pancreatic neuroendocrine tumors (PNETs) using whole-genome and transcriptome sequencing

Pancreatic neuroendocrine tumors (PNETs) are a genomically and clinically heterogeneous group of pancreatic neoplasms often diagnosed with distant metastases. Recurrent somatic mutations, chromosomal aberrations, and gene expression signatures in PNETs have been described, but the clinical significa...

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Vydáno v:Cold Spring Harb Mol Case Stud
Hlavní autoři: Wong, Hui-li, Yang, Kevin C., Shen, Yaoqing, Zhao, Eric Y., Loree, Jonathan M., Kennecke, Hagen F., Kalloger, Steve E., Karasinska, Joanna M., Lim, Howard J., Mungall, Andrew J., Feng, Xiaolan, Davies, Janine M., Schrader, Kasmintan, Zhou, Chen, Karsan, Aly, Jones, Steven J.M., Laskin, Janessa, Marra, Marco A., Schaeffer, David F., Gorski, Sharon M., Renouf, Daniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5793777/
https://ncbi.nlm.nih.gov/pubmed/29092957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a002329
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