Correlated levels of cerebrospinal fluid pathogenic proteins in drug-naïve Parkinson’s disease

BACKGROUND AND AIM: Toxic oligomeric α-synuclein (αS; O-αS) has been suggested to play a central role in the pathogenesis of Lewy body diseases such as Parkinson’s disease (PD). Cerebrospinal fluid (CSF) levels of αS, O-αS, total and phosphorylated tau, and amyloid β 1–42 (Aβ1–42) are thought to ref...

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Detalhes bibliográficos
Publicado no:BMC Neurol
Main Authors: Murakami, Hidetomo, Tokuda, Takahiko, El-Agnaf, Omar M. A., Ohmichi, Takuma, Miki, Ayako, Ohashi, Hideaki, Owan, Yoshiyuki, Saito, Yu, Yano, Satoshi, Tsukie, Tamao, Ikeuchi, Takeshi, Ono, Kenjiro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549316/
https://ncbi.nlm.nih.gov/pubmed/31164098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12883-019-1346-y
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