PRP-1 significantly decreases the ALDH(high) cancer stem cell population and regulates the aberrant Wnt/β-catenin pathway in human chondrosarcoma JJ012 cells

Chondrosarcomas are malignant bone tumors refractory to chemotherapy and radiation treatment; thus, novel therapeutic strategies are required. Proline-rich polypeptide 1 (PRP-1) has previously demonstrated antitumor properties in chondrosarcoma. To further investigate the role of PRP-1 in chondrosar...

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Udgivet i:Oncol Rep
Main Authors: Hoyt, A.K., Moran, A., Granger, C., Sedani, A., Saigh, S., Brown, J., Galoian, K.A.
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2019
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549102/
https://ncbi.nlm.nih.gov/pubmed/31180539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2019.7172
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