Cancer stem cells as a therapeutic target in 3D tumor models of human chondrosarcoma: An encouraging future for proline rich polypeptide-1

Chondrosarcoma is a malignant bone neoplasm that is refractory to chemotherapy and radiation. With no current biological treatments, mutilating surgical resection is the only effective treatment. Proline rich polypeptide 1 (PRP-1), which is a 15-amino acid inhibitor of mammalian target of rapamycin...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Granger, Caroline J., Hoyt, Aaron K., Moran, Alexandra, Becker, Beatrice, Sedani, Anil, Saigh, Shannon, Conway, Sheila A., Brown, Jeffrey, Galoian, Karina
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533489/
https://ncbi.nlm.nih.gov/pubmed/32901865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11480
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