The Wnt/β-Catenin/LEF1 Pathway Promotes Cell Proliferation at Least in Part Through Direct Upregulation of miR-17-92 Cluster

The miR-17-92 cluster is involved in animal development and homeostasis, and its dysregulation leads to human diseases such as cancer. In the present study, we investigated the functional link between miR-17-92 cluster and Wnt/β-catenin signaling pathway in ICP2 and DF1 cells. We demonstrated that e...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Mu, Fang, Huang, Jiaxin, Xing, Tianyu, Jing, Yang, Cui, Tingting, Guo, Yaqi, Yan, Xiaohong, Li, Hui, Wang, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549003/
https://ncbi.nlm.nih.gov/pubmed/31191623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00525
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