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Upregulation of the miR-17-92 cluster and its two paraloga in osteosarcoma – reasons and consequences

Osteosarcomas (OS) are aggressive bone tumors characterized by complex karyotypes with highly variable structural and numerical chromosomal aberrations. Although several genes and pathways commonly altered in malignant tumors have also been identified in OS, the molecular pathogenesis and driving ge...

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Détails bibliographiques
Auteurs principaux: Arabi, Leila, Gsponer, Joël R, Smida, Jan, Nathrath, Michaela, Perrina, Valeria, Jundt, Gernot, Ruiz, Christian, Quagliata, Luca, Baumhoer, Daniel
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063253/
https://ncbi.nlm.nih.gov/pubmed/24955218
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