Upregulation of the miR-17-92 cluster and its two paraloga in osteosarcoma – reasons and consequences

Osteosarcomas (OS) are aggressive bone tumors characterized by complex karyotypes with highly variable structural and numerical chromosomal aberrations. Although several genes and pathways commonly altered in malignant tumors have also been identified in OS, the molecular pathogenesis and driving ge...

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Detalhes bibliográficos
Main Authors: Arabi, Leila, Gsponer, Joël R, Smida, Jan, Nathrath, Michaela, Perrina, Valeria, Jundt, Gernot, Ruiz, Christian, Quagliata, Luca, Baumhoer, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063253/
https://ncbi.nlm.nih.gov/pubmed/24955218
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