Effective Delivery of Hypertrophic miRNA Inhibitor by Cholesterol‐Containing Nanocarriers for Preventing Pressure Overload Induced Cardiac Hypertrophy

Persistent cardiac hypertrophy causes heart failure and sudden death. Gene therapy is a promising intervention for this disease, but is limited by the lack of effective delivery systems. Herein, it is reported that CHO‐PGEA (cholesterol (CHO)‐terminated ethanolamine‐aminated poly(glycidyl methacryla...

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Publicat a:Adv Sci (Weinh)
Autors principals: Zhi, Ying, Xu, Chen, Sui, Dandan, Du, Jie, Xu, Fu‐Jian, Li, Yulin
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Full Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548964/
https://ncbi.nlm.nih.gov/pubmed/31179215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201900023
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