Bioactivity of Farnesyltransferase Inhibitors Against Entamoeba histolytica and Schistosoma mansoni

The protozoan parasite Entamoeba histolytica can induce amebic colitis and amebic liver abscess. First-line drugs for the treatment of amebiasis are nitroimidazoles, particularly metronidazole. Metronidazole has side effects and potential drug resistance is a concern. Schistosomiasis, a chronic and...

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Bibliographic Details
Published in:Front Cell Infect Microbiol
Main Authors: Probst, Alexandra, Nguyen, Thi N., El-Sakkary, Nelly, Skinner, Danielle, Suzuki, Brian M., Buckner, Frederick S., Gelb, Michael H., Caffrey, Conor R., Debnath, Anjan
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Cellular and Infection Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548881/
https://ncbi.nlm.nih.gov/pubmed/31192168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00180
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