Function of Human Tumor-Infiltrating Lymphocytes in Early Stage Non-Small Cell Lung Cancer

Cancer progression is marked by dysfunctional tumor-infiltrating lymphocytes (TILs) with high inhibitory receptor (IR) expression. Since inhibitory receptor blockade has led to clinical responses in some non-small cell lung cancer (NSCLC) patients, we investigated how IRs influenced CD8(+) TIL funct...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: O’Brien, Shaun M., Klampatsa, Astero, Thompson, Jeffrey C., Martinez, Marina C., Hwang, Wei-Ting, Rao, Abishek S., Standalick, Jason E., Kim, Soyeon, Cantu, Edward, Litzky, Leslie A., Singhal, Sunil, Eruslanov, Evgeniy B., Moon, Edmund K., Albelda, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548666/
https://ncbi.nlm.nih.gov/pubmed/31053597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0713
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