The role of G-quadruplex structures of LIGS-generated aptamers R1.2 and R1.3 in IgM specific recognition

Exploiting a variant of SELEX called “Ligand-Guided Selection” (LIGS), we recently identified two novel truncated G-rich aptamers, called R1.2 and R1.3, specific for membrane bound IgM (mIgM), the hallmark of B cells. Herein, the conformational behaviour of these aptamers has been analysed by multip...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Biol Macromol
Hauptverfasser: Moccia, Federica, Platella, Chiara, Musumeci, Domenica, Batool, Sana, Zumrut, Hasan, Bradshaw, John, Mallikaratchy, Prabodhika, Montesarchio, Daniela
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548653/
https://ncbi.nlm.nih.gov/pubmed/31022491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijbiomac.2019.04.141
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