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Glutamine addiction: an Achilles heel in esophageal cancers with dysregulation of CDK4/6
Understanding and overcoming resistance to cyclin-dependent kinase 4/6 (CDK4/6) inhibitors will be challenging. Recent work reveals that dysregulation of F-Box Protein 4 (FBXO4)-Cyclin D1 axis leads to mitochondrial dysfunction and drives glutamine-addiction in esophageal squamous cell carcinoma. Th...
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| Publicado en: | Mol Cell Oncol |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6548481/ https://ncbi.nlm.nih.gov/pubmed/31211239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1610257 |
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