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JmjC histone demethylases act as chromatin oxygen sensors

Oxygen sensing is important in physiology but also in disease. We find that hypoxia (oxygen deficiency) triggers rapid and hypoxia-inducible factor (HIF)-independent histone methylation changes which are reversible upon reoxygenation. Hypoxia-induced histone methylation genomic distribution precedes...

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Publicat a:Mol Cell Oncol
Autors principals: Batie, Michael, Rocha, Sonia
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548480/
https://ncbi.nlm.nih.gov/pubmed/31211238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1608501
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