SPATIALLY-RESTRICTED STROMAL WNT SIGNALING RESTRAINS PROSTATE EPITHELIAL PROGENITOR PROLIFERATION THROUGH DIRECT AND INDIRECT MECHANISMS

Cell-autonomous Wnt signaling has well-characterized functions in controlling stem cell activity, including in the prostate. While niche cells secrete Wnt ligands, the effects of Wnt signaling in niche cells per se are less understood. Here we show that stromal cells in the proximal prostatic duct n...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Wei, Xing, Zhang, Li, Zhou, Zhicheng, Kwon, Oh-Joon, Zhang, Yiqun, Nguyen, Hoang, Dumpit, Ruth, True, Lawrence, Nelson, Peter, Dong, Baijun, Xue, Wei, Birchmeier, Walter, Taketo, Makoto, Xu, Feng, Creighton, Chad J, Ittmann, Michael M, Xin, Li
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548441/
https://ncbi.nlm.nih.gov/pubmed/30982770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.03.010
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