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Inhibition by fluoxetine of LH-stimulated cyclic AMP synthesis in tumor Leydig cells partly involves AMPK activation

Fluoxetine (FLX), a widely used antidepressant primarily acting as a selective serotonin reuptake inhibitor (SSRI), has been shown to exhibit other mechanisms of action in various cell types. Consequently, it might have unexpected adverse effects not related to its intended use, possibly in the endo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nguyen, Thi Mong Diep, Klett, Danièle, Filliatreau, Laura, Combarnous, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548379/
https://ncbi.nlm.nih.gov/pubmed/31163038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217519
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