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Inhibition by fluoxetine of LH-stimulated cyclic AMP synthesis in tumor Leydig cells partly involves AMPK activation

Fluoxetine (FLX), a widely used antidepressant primarily acting as a selective serotonin reuptake inhibitor (SSRI), has been shown to exhibit other mechanisms of action in various cell types. Consequently, it might have unexpected adverse effects not related to its intended use, possibly in the endo...

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Publicat a:PLoS One
Autors principals: Nguyen, Thi Mong Diep, Klett, Danièle, Filliatreau, Laura, Combarnous, Yves
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548379/
https://ncbi.nlm.nih.gov/pubmed/31163038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217519
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