Severe fever with thrombocytopenia syndrome phlebovirus non-structural protein activates TPL2 signalling pathway for viral immunopathogenesis

Severe fever with thrombocytopenia syndrome phlebovirus (SFTSV), listed in the World Health Organization Prioritized Pathogens, is an emerging phlebovirus with a high fatality(1–4). Owing to the lack of therapies and vaccines(5,6), there is a pressing need to understand SFTSV pathogenesis. SFSTV non...

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Pubblicato in:Nat Microbiol
Autori principali: Choi, Younho, Park, Su-Jin, Sun, Yinyan, Yoo, Ji-Seung, Pudupakam, Raghavendra Sumanth, Foo, Suan-Sin, Shin, Woo-Jin, Chen, Sally B., Tsichlis, Philip N., Lee, Won-Ja, Lee, Jong-Soo, Li, Wenhui, Brennan, Benjamin, Choi, Young-Ki, Jung, Jae U.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548314/
https://ncbi.nlm.nih.gov/pubmed/30617349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-018-0329-x
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