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UBE3A regulates the transcription of IRF, an antiviral immunity

UBE3A is a gene responsible for the pathogenesis of Angelman syndrome (AS), a neurodevelopmental disorder characterized by symptoms such as intellectual disability, delayed development and severe speech impairment. UBE3A encodes an E3 ubiquitin ligase, for which several targets have been identified,...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Furumai, Ryohei, Tamada, Kota, Liu, Xiaoxi, Takumi, Toru
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548221/
https://ncbi.nlm.nih.gov/pubmed/30690483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz019
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