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Respiratory chain inactivation links cartilage-mediated growth retardation to mitochondrial diseases
In childhood, skeletal growth is driven by transient expansion of cartilage in the growth plate. The common belief is that energy production in this hypoxic tissue mainly relies on anaerobic glycolysis and not on mitochondrial respiratory chain (RC) activity. However, children with mitochondrial dis...
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| 出版年: | J Cell Biol |
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| 主要な著者: | , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Rockefeller University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6548139/ https://ncbi.nlm.nih.gov/pubmed/31085560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201809056 |
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