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Necroptosis mediators RIPK3 and MLKL suppress intracellular Listeria replication independently of host cell killing

RIPK3, a key mediator of necroptosis, has been implicated in the host defense against viral infection primary in immune cells. However, gene expression analysis revealed that RIPK3 is abundantly expressed not only in immune organs but also in the gastrointestinal tract, particularly in the small int...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Sai, Kazuhito, Parsons, Cameron, House, John S., Kathariou, Sophia, Ninomiya-Tsuji, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548127/
https://ncbi.nlm.nih.gov/pubmed/30975711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201810014
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