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Autoantigens as partners in initiation and propagation of autoimmune rheumatic diseases

Systemic autoimmune diseases are characterized by specific targeting of a limited group of ubiquitously expressed autoantigens by the immune system. This chapter examines the mechanisms underlying their selection as immune targets. Initiation of autoimmune responses likely reflects the presentation...

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Pubblicato in:Annu Rev Immunol
Autori principali: Rosen, Antony, Casciola-Rosen, Livia
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547816/
https://ncbi.nlm.nih.gov/pubmed/26907212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-immunol-032414-112205
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