Unraveling the identity of FoxP3+ regulatory T cells in Granulomatosis with Polyangiitis patients

Human CD4(+)FoxP3(+)T-cells are heterogeneous in function and include not only suppressive cells (Tregs), but also effector cells that transiently express FoxP3 upon activation. Previous studies in Granulomatosis with Polyangiitis (GPA-)patients have demonstrated an increase in FoxP3(+)T-cells with...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Reijnders, Tom D. Y., Stegeman, Coen A., Huitema, M. G., Rutgers, Abraham, Heeringa, Peter, Abdulahad, Wayel H.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547679/
https://ncbi.nlm.nih.gov/pubmed/31164680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44636-y
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