Sialyl Lewis(x)-P-selectin cascade mediates tumor–mesothelial adhesion in ascitic fluid shear flow

Organ-specific colonization suggests that specific cell–cell recognition is essential. Yet, very little is known about this particular interaction. Moreover, tumor cell lodgement requires binding under shear stress, but not static, conditions. Here, we successfully isolate the metastatic populations...

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Pubblicato in:Nat Commun
Autori principali: Li, Shan-Shan, Ip, Carman K. M., Tang, Matthew Y. H., Tang, Maggie K. S., Tong, Yin, Zhang, Jiangwen, Hassan, Ayon Ahmed, Mak, Abby S. C., Yung, Susan, Chan, Tak-Mao, Ip, Philip P., Lee, Cheuk Lun, Chiu, Philip C. N., Lee, Leo Tsz On, Lai, Hung-Cheng, Zeng, Jin-Zhang, Shum, Ho Cheung, Wong, Alice S. T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547673/
https://ncbi.nlm.nih.gov/pubmed/31160622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10334-6
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