Sialyl Lewis(x)-P-selectin cascade mediates tumor–mesothelial adhesion in ascitic fluid shear flow

Organ-specific colonization suggests that specific cell–cell recognition is essential. Yet, very little is known about this particular interaction. Moreover, tumor cell lodgement requires binding under shear stress, but not static, conditions. Here, we successfully isolate the metastatic populations...

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Udgivet i:Nat Commun
Main Authors: Li, Shan-Shan, Ip, Carman K. M., Tang, Matthew Y. H., Tang, Maggie K. S., Tong, Yin, Zhang, Jiangwen, Hassan, Ayon Ahmed, Mak, Abby S. C., Yung, Susan, Chan, Tak-Mao, Ip, Philip P., Lee, Cheuk Lun, Chiu, Philip C. N., Lee, Leo Tsz On, Lai, Hung-Cheng, Zeng, Jin-Zhang, Shum, Ho Cheung, Wong, Alice S. T.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547673/
https://ncbi.nlm.nih.gov/pubmed/31160622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10334-6
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