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Endo-lysosomal dysregulations and late-onset Alzheimer’s disease: impact of genetic risk factors

Increasing evidence supports that cellular dysregulations in the degradative routes contribute to the initiation and progression of neurodegenerative diseases, including Alzheimer’s disease. Autophagy and endolysosomal homeostasis need to be maintained throughout life as they are major cellular mech...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Van Acker, Zoë P., Bretou, Marine, Annaert, Wim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547588/
https://ncbi.nlm.nih.gov/pubmed/31159836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-019-0323-7
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