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Bacterial Ligase D preternary-precatalytic complex performs efficient abasic sites processing at double strand breaks during nonhomologous end joining

Abasic (AP) sites, the most common DNA lesions are frequently associated with double strand breaks (DSBs) and can pose a block to the final ligation. In many prokaryotes, nonhomologous end joining (NHEJ) repair of DSBs relies on a two-component machinery constituted by the ring-shaped DNA-binding Ku...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: de Ory, Ana, Carabaña, Claudia, de Vega, Miguel
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547435/
https://ncbi.nlm.nih.gov/pubmed/30976810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz265
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