Stem Cell Proliferation Is Kept in Check by the Chromatin Regulators Kismet/CHD7/CHD8 and Trr/MLL3/4

Chromatin remodeling accompanies differentiation, however, its role in self-renewal is less well understood. We report that in Drosophila, the chromatin remodeler Kismet/CHD7/CHD8 limits intestinal stem cell (ISC) number and proliferation without affecting differentiation. Stem-cell-specific whole-g...

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發表在:Dev Cell
Main Authors: Gervais, Louis, van den Beek, Marius, Josserand, Manon, Sallé, Jérémy, Stefanutti, Marine, Perdigoto, Carolina N., Skorski, Patricia, Mazouni, Khallil, Marshall, Owen J., Brand, Andrea H., Schweisguth, François, Bardin, Allison J.
格式: Artigo
語言:Inglês
出版: Cell Press 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547167/
https://ncbi.nlm.nih.gov/pubmed/31112698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.04.033
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