Spen limits intestinal stem cell self-renewal

Precise regulation of stem cell self-renewal and differentiation properties is essential for tissue homeostasis. Using the adult Drosophila intestine to study molecular mechanisms controlling stem cell properties, we identify the gene split-ends (spen) in a genetic screen as a novel regulator of int...

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Dettagli Bibliografici
Pubblicato in:PLoS Genet
Autori principali: Andriatsilavo, Maheva, Stefanutti, Marine, Siudeja, Katarzyna, Perdigoto, Carolina N., Boumard, Benjamin, Gervais, Louis, Gillet-Markowska, Alexandre, Al Zouabi, Lara, Schweisguth, François, Bardin, Allison J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277126/
https://ncbi.nlm.nih.gov/pubmed/30452449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007773
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