A β2-Integrin/MRTF-A/SRF Pathway Regulates Dendritic Cell Gene Expression, Adhesion, and Traction Force Generation

β2-integrins are essential for immune system function because they mediate immune cell adhesion and signaling. Consequently, a loss of β(2)-integrin expression or function causes the immunodeficiency disorders, Leukocyte Adhesion Deficiency (LAD) type I and III. LAD-III is caused by mutations in an...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Guenther, Carla, Faisal, Imrul, Uotila, Liisa M., Asens, Marc Llort, Harjunpää, Heidi, Savinko, Terhi, Öhman, Tiina, Yao, Sean, Moser, Markus, Morris, Stephan W., Tojkander, Sari, Fagerholm, Susanna Carola
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546827/
https://ncbi.nlm.nih.gov/pubmed/31191527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01138
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