microRNA-21-5p dysregulation in exosomes derived from heart failure patients impairs regenerative potential

Exosomes, as functional paracrine units of therapeutic cells, can partially reproduce the reparative properties of their parental cells. The constitution of exosomes, as well as their biological activity, largely depends on the cells that secrete them. We isolated exosomes from explant-derived cardi...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Qiao, Li, Hu, Shiqi, Liu, Suyun, Zhang, Hui, Ma, Hong, Huang, Ke, Li, Zhenhua, Su, Teng, Vandergriff, Adam, Tang, Junnan, Allen, Tyler, Dinh, Phuong-Uyen, Cores, Jhon, Yin, Qi, Li, Yongjun, Cheng, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546482/
https://ncbi.nlm.nih.gov/pubmed/31033484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI123135
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