microRNA-21-5p dysregulation in exosomes derived from heart failure patients impairs regenerative potential

Exosomes, as functional paracrine units of therapeutic cells, can partially reproduce the reparative properties of their parental cells. The constitution of exosomes, as well as their biological activity, largely depends on the cells that secrete them. We isolated exosomes from explant-derived cardi...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Qiao, Li, Hu, Shiqi, Liu, Suyun, Zhang, Hui, Ma, Hong, Huang, Ke, Li, Zhenhua, Su, Teng, Vandergriff, Adam, Tang, Junnan, Allen, Tyler, Dinh, Phuong-Uyen, Cores, Jhon, Yin, Qi, Li, Yongjun, Cheng, Ke
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546482/
https://ncbi.nlm.nih.gov/pubmed/31033484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI123135
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