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Anti–neurofascin-155 IgG4 antibodies prevent paranodal complex formation in vivo
Neurofascin-155 (Nfasc155) is an essential glial cell adhesion molecule expressed in paranodal septate-like junctions of peripheral and central myelinated axons. The genetic deletion of Nfasc155 results in the loss of septate-like junctions and in conduction slowing. In humans, IgG4 antibodies again...
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| Udgivet i: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6546478/ https://ncbi.nlm.nih.gov/pubmed/30869655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI124694 |
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