Lactococcus lactis type III-A CRISPR-Cas system cleaves bacteriophage RNA

CRISPR-Cas defends microbial cells against invading nucleic acids including viral genomes. Recent studies have shown that type III-A CRISPR-Cas systems target both RNA and DNA in a transcription-dependent manner. We previously found a type III-A system on a conjugative plasmid in Lactococcus lactis...

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Bibliografski detalji
Izdano u:RNA Biol
Glavni autori: Millen, Anne M., Samson, Julie E., Tremblay, Denise M., Magadán, Alfonso H., Rousseau, Geneviève M., Moineau, Sylvain, Romero, Dennis A.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2018
Teme:
Brief Communication
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546414/
https://ncbi.nlm.nih.gov/pubmed/30081743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1502589
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